Although you should avoid going longer than 3-4 days without sleep, you can safely stay up for a few days as long as you plan to get full nights of sleep for 1-2 days afterwards. I once stayed up for four days in grad school to finish some projects. I tried switching on the TV, hoping I'd get sleepy and just doze off. Exercise will also help you sleep better at night. Some people said I looked like death others just did a double take stare like they saw a zombie. Don’t binge eat after. I'm not really anxious or stressed. Science says this is actually a good thing to do occasionally. I like the answers you received and just have one question. Been there myself many times... As for the 'dire consequences' of a lack of sleep, as a medical layman I say to you: don't worry about it excessively. I remember one time I had to take steroids for a week. If you have been able to sleep well before, the first thing to do is to figure out what may recently have changed. Lasted about 3-4 weeks. So I actually have recent experience with this. It feels normal, then gets bad, then normal again like nothing happened and in the end it's heavenly, let me walk you through it. X Research source With a little bit of preparation and a regular schedule, you'll be able to stay awake and push through to the end. I feel your pain..! And those changes should help you survive the day. After the first night, I couldn’t sleep. Also you will be hungry. It got harder and harder to stay awake, By day three I started hallucinating. I'm miserable. … after a few years you graduate with a degree in medicine. I haven't slept in about 48 hours. I'm tired, but I just cannot get to sleep. Does your doctor have you on any type of steroid medication? Seriously, though, welcome to the world of quite a few professions during their university years. Lots of coffee, loud music, brisk walks, and utter desperation. No big deal. sleep effects the chemistry of the body so a dramatic shift in sleep pattern will produce the effect you describe. You probably will lose some mental and physiological defense systems. This may give you a clue as to the reason for your insomnia: * New supplements, medications, foods, beverages? I've layed in bed for hours. I have been taking Melatonin or Lorazepam and neither seems to work for me. Is this still a problem ?! I've tried laying down and going to sleep, but its like trying to go to bed when you're totally wide awake. With multiple deployments under his belt, Kelley has had many instances of … TLDR: Not a whole heck of a lot that you can tell. At this point the muscle fatigue is really bad to the point that even sitting up is just... heavy. My body is ready for bed, but my brain is not. I slept but only about 15-20 minutes a day of real sleep. Scott Kelley, a 10-year Army veteran, knows about sleep deprivation. 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